T2386
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T2386
Sigma
Δ9-Tetrahydrocannabinol solution
ethanol solution
| Synonym: | Δ1-Tetrahydrocannabinol |
| CAS Number: | 1972-08-3 |
| Linear Formula: | C21H30O2 |
| Molecular Weight: | 314.46 |
| MDL number: | MFCD00083207 |
| PubChem Substance ID: | 24900035 |
Description
| Biochem/physiol Actions | Agonist at CB1 and CB2 cannabinoid receptors. Hallucinogen; major psychoactive component of marijuana from Cannabis sativa. |
Properties
| form | ethanol solution |
| drug control | USDEA Schedule I; Home Office Schedule 2; stupéfiant; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada |
| concentration | ~25 mg/mL |
| Gene Information | human ... CNR2(1269) |
| rat ... Cnr1(25248) | |
| mouse ... Cnr1(12801) | |
| storage temp. | −20°C |
Safety
| Personal Protective Equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
| Hazard Codes | F |
| Risk Statements | 11 |
| Safety Statements | 16 |
| RIDADR | UN 1170 3/PG 2 |
| WGK Germany | 1 |
References
| reference | Rodriguez de Fonseca, F., et al., Effects of Δ9-THC on VIP-induced prolactin secretion in anterior pituitary cultures: evidence for the presence of functional cannabinoid CB1 receptors in pituitary cells. Brain Res. 841, 114-122, (1999) |
| Mason, D.J. Jr, et al., Cannabinoid modulation of dynorphin A: correlation to cannabinoid-induced antinociception. Eur. J. Pharmacol. 378, 237-248, (1999) | |
| Tanda, G., et al., Dependence of mesolimbic dopamine transmission on Δ9-tetrahydrocannabinol. Eur. J. Pharmacol. 376, 23-36, (1999) |
